MGC Life Science, as the exclusive representative of ChargePoint Technology in Brazil, a British company specializing in transfer systems for high-containment and aseptic applications, provides active/passive transfer systems that enable completely closed transfers, preventing exposure of the environment and the product during operation. These systems, mostly composed of a butterfly valve (active system) and a transfer interface (passive system / e.g., BIN), offer greater safety and practicality in high-containment applications and sterile processes.
We have a trained technical team in Brazil to guarantee the maintenance of systems operating in the country, and in the case of high-containment applications, we can provide certification according to the APCPPE (SMEPAC) guide.
ChargePoint products are the ideal solution for industries seeking to:
ChargePoint Technology’s powder transfer systems for aseptic applications offer enhanced sterility assurance when handling active pharmaceutical and biotechnological ingredients in aseptic environments (filling, finishing, and production).
This is achieved through AseptiSafe®Bio split butterfly valve assemblies.
This patented ChargePoint technology uses an enhanced decontamination step in the process to deliver a validated 6-log reduction.
During the product transfer process using the valve, prior to product transfer, the disc faces of the Bio valve are exposed to decontamination gases within a sealed chamber to ensure decontamination of all critical areas, effectively and quickly killing organisms while protecting the product from the decontamination gases.
The AseptiSafe®Bio system:
ChargePoint Technology’s powder transfer systems for high-containment applications offer the highest levels of operator/environmental protection through validated containment performance. These solutions are essential when handling high-potency active pharmaceutical ingredients (HPAPIs), such as antineoplastics, hormones, antibiotics, and others.
The desired result is achieved through PharmaSafe® high-containment split butterfly valve assemblies. These provide safe handling, achieving containment levels in the nanogram per cubic meter range of air.
ChargePoint’s PharmaSafe® valve line is the ideal solution for transferring highly potent powder products, whether in small or large quantities. This unique valve technology provides numerous benefits, including reduced contamination risk, meeting GMP/product quality requirements, increased transfer throughput for low-flow, high-value products, and eliminating costly secondary barrier containment and heavy PPE.
The three valves in the PharmaSafe® line include:
The containment performance of PharmaSafe® valves has been independently validated by customers and third parties, in accordance with ISPE SMEPAC guidelines.
ChargePoint Technology’s single-use disposable powder transfer systems are the ideal solution for aseptic and high-containment transfers, where the goal is to reduce the risks associated with cross-contamination and eliminate the time and expense associated with cleaning and validation.
To this end, one of ChargePoint’s key solutions is the use of the ChargeBag® PE-S, a high-integrity powder transfer bag ideal for sterile processing. This disposable option is a cost-effective and convenient solution for handling, storing, and transferring biopharmaceutical powders.
Each ChargeBag® PE-S is manufactured with high levels of quality control in an ISO 6 cleanroom environment. Each ChargeBag® is tested with 100% pressure decay to ensure integrity and supplied with gamma sterilization ready for use in aseptic facilities and many other cGMP manufacturing facilities. This consumable has been extensively qualified according to the most stringent chemical, biological, and physical compliance standards and offers a complete data profile characteristic of a wide range of products and process conditions.
The ChargeBag® PE-S is manufactured with HiPure ULP7, ChargePoint’s pharmaceutical-grade ready-to-use LLDPE film. HiPure ULP7 is manufactured with extremely high levels of integrity related to regulatory qualification, as well as robustness with excellent mechanical strength and antistatic properties, providing performance and purity for the safety of products and people.
The ChargeBag® PE-S is also available as part of a complete single-use transfer solution, with a ChargePoint single-use bi-part passive butterfly valve welded directly onto the ChargeBag® assembly, offering high levels of containment performance and sterility assurance.
